Fred Lewis is a six-time U.S. National Four-Wall Handball Singles Champion, and 3-time National Three-Wall Singles Champion - all between 1972 and 1981. He was inducted into the Handball Hall of Fame in 1993.

For the 1970's, Lewis was named "Handball Player of the Decade". He played in a National Open Singles Final or Doubles Final (four-wall or three-wall) every year of that decade. In all, he made the finals of the National Open championship 14 consecutive years.

Lewis captured two U.S. National Collegiate Singles Championships (as a University of Miami student), and won 16 titles on the professional tour.